This course provides a comprehensive understanding of biosafety applied to equine production and management. It covers key concepts on the prevention of biological, chemical, and physical hazards, emphasizing the importance of implementing standards and procedures for the protection of personnel, animals, and the environment. Biosafety levels according to international standards will be analyzed, along with contaminants and their impact on equine and human health. Furthermore, strategies for minimizing contamination in breeding programs and general management will be explored, promoting a preventive and controlled approach to equine health.